Hemp Residual Solvent Screening (National Coverage)

ACS Laboratory offers a GC-MS residual solvent test that screens for 55 to 67 analytes in one run. This max-analyte panel can satisfy the strictest U.S. state requirements, so hemp brands nationwide can feel confident bringing products to market.
Our residual solvents testing detects common extraction chemicals, including butane and ethanol, to verify clean products. Brands use this panel for solvent screening in hemp extracts during R&D and to confirm national compliance across multiple state limits.

Safety Panels:

Why Residual Solvent Testing Matters (Class 1–3)

Residual solvents can remain in hemp and cannabis extracts after the production of wax, oils, or concentrates. Some are highly toxic, others have limited use, and a few pose low risks. Understanding the classes and performing class 1 solvent testing cannabis is critical for safety, COA review, and retailer acceptance.

 Class 1 – Highly toxic:

Includes benzene, a known carcinogen. Class 1 solvent testing cannabis is essential because no safe exposure threshold exists.

Class 2 – Limited use:

Includes chloroform, methanol, toluene, and n-butane. These compounds are permitted only at low ppm levels and require careful monitoring.

Class 3 – Low toxic potential:

Includes ethanol, acetone, and n-pentane. Though rules vary by state, these solvents are generally safe at higher ppm thresholds.

Cannabis residual solvent testing with an ISO/IEC 17025:2017 A2LA-accredited laboratory like ACS ensures products meet action limits and pass compliance reviews.

Preventing Contamination in Extraction

Even the most consistent extraction process can leave behind trace solvents when conditions vary between runs.  Products like shatter or wax are especially difficult to purge because their surface area makes it harder for solvents to evaporate.

Producers can reduce contamination risks by refining evaporation methods, extending purge times, and applying deeper vacuum cycles. Still, no method eliminates variability in natural plant material. The most reliable way to protect patients and consumers is to partner with an ISO/IEC 17025:2017 A2LA accredited laboratory like ACS for regular residual solvent testing.