Comparing Exotic Cannabinoids: Delta-9 THC vs. Delta-8, Delta-10, HHC, HHCP, THC-O (THCOa), & THCP

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Comparing Exotic Cannabinoids: Delta-9 THC vs. Delta-8, Delta-10, HHC, HHCP, THC-O (THCOa), & THCP

Most people know Delta-9 THC, the famous and illicit cannabinoid simply called “THC.” However, only a few aficionados truly understand exotic cannabinoids like Delta-8 THC, Delta-10 THC, HHC, THCOa(THCO), and THCP. 

These novel cannabinoids are all psychoactive, and some exist naturally in hemp and cannabis plants, like Delta-9. However, most exotic cannabinoids are semi-synthetically made and have unique qualities that consumers need to understand. The main difference between exotic cannabinoids and Delta-9 THC is how they occur, their molecular structures, psychoactive intensity, and legality.

Here we compare today’s top trending exotic cannabinoids so consumers can make the most informed decisions.

What Is Delta-8 THC?

Delta-8 THC is an exotic cannabinoid found in cannabis and hemp plants in trace amounts.

Delta-8 products are semi-synthetic, unleashing psychoactive effects like Delta-9 THC with unique qualities.

Delta-8 THC Experience

Delta-8 produces a mild psychoactive experience that users describe as calming and euphoric. Delta-8 can reduce feelings of nausea and provides many known benefits of THC. In one study, 71% of Delta-8 users reported relaxation, 68% experienced euphoria, and more than 50% got relief from pain. 

Delta-8 compared to Delta-9

Delta-8 appears to have a lower affinity for the brain’s CB1 receptor, making it less potent than Delta-9 THC. Most consumers say Delta-8 is noticeably milder than Delta-9 and has an “indica-like” high due to its sedative properties. Its lower potency also means Delta-8 is less likely to cause adverse effects, such as paranoia.

Molecular Structure

Delta-8 and Delta-9 have the same molecular formula with different atomic arrangements. Both cannabinoids contain a double-carbon bond but on different atom rings. In Delta-8, the double carbon bond falls on the 8th atom ring, while Delta-9’s falls on the 9th—hence the names. Scientists believe this difference partly explains Delta-8’s effects and potency variation.

Cannabinoid Type: THC isomer

How Are Delta-8 Products Made?

Delta-8 THC is a byproduct of plant degradation. When cannabis is exposed to heat, its Delta 9 THC content breaks down through a process called decarboxylation and trace amounts transform into Delta-8. However, Delta-8 products are not natural extracts. Most Delta-8 products are synthesized from CBD.

Processors extract CBD from hemp and convert it into Delta-8 THC using a blend of chemical solvents (like heptane) and acids (like hydrochloric) in a process called “isomerization.”

Delta-8 Hemp and Cannabis Products

Delta-8 is one of the fastest-growing compounds on the hemp market. It’s available in many cannabis and hemp-based products that consumers can inhale, ingest, and apply topically, including:

  • Distillate cartridges
  • Distillate syringes
  • Vape cartridges
  • Tinctures
  • Oils
  • Concentrates
  • Gummies and edibles
  • Beverages
  • Flower (sprayed with Delta-8 distillate)

Delta-8 Legality: Updated October 2022

Delta-8 is federally legal. However, due to its production methods and lack of comprehensive legislation, many states have introduced bills that explicitly prohibit Delta-8 and other exotic cannabinoids made through isomerization. So far, 17 states, including Colorado, Washington, New York, and Michigan, have banned Delta-8. Check out our State-by-State Delta-8 Legality Guide for the latest updates. 

What Is Delta-10 THC?

Delta-10 THC, like Delta-8 occurs as byproduct of plant degradation. Delta-10 products are semi-synthetic, and their effects tend to be more energizing and less potent than other THC isomers. 

Delta-10 THC Experience

Delta-10 users report an uplifting and energizing experience with a gentle head buzz. Reddit users claim similar effects to Delta-8 THC, albeit less potent, likening Delta-10 to a Sativa strain’s “mind high” instead of a physical body high. Many describe Delta-10 as a great daytime product that enhances motivation, creativity, and cognitive function. 

Delta-10 compared to Delta-9

Delta-10 is less potent than Delta-9, likely due to a weaker binding affinity to receptors in the endocannabinoid system. Delta-10 offers euphoria and increased focus with buzzy, energizing qualities similar to a Sativa strain but without the paranoia and anxiety some users report from Delta-9.

Molecular Structure

Delta-10 and Delta-9 have nearly identical chemical structures with double carbon atom rings. However, that bond occurs on the 9th atom ring in Delta-9 and on the 10th ring in Delta-10, hence their respective names. This atomic similarity makes Delta-10 a THC isomer. 

Molecule Type: THC isomer 

How Are Delta-10 Products Made?

Delta-10, like Delta-8, appears in trace quantities in cannabis plants. As a result, manufacturers can’t extract enough to make products. So they utilize an isomerization process similar to Delta-8. Here’s how it works: Producers usually extract hemp-derived CBD using chemical solvents and convert the CBD into Delta-10 using solvents and acids. 

Delta-10 Hemp and Cannabis Products

Delta-10 products are increasingly popular, and many product types are on the market for users to vape and ingest. Delta-10 cannabis and hemp-derived products include:

  • Disposable pens
  • Vape cartridges
  • Gummies
  • Tinctures and oils 
  • Dabbing syringes
  • Chocolate bars
  • Lollipops
  • Shatter 
  • Flower and pre-rolls (sprayed with Delta-10 distillate)

Delta-10 Legality

Delta-10 products are federally legal under the 2018 Farm Bill if sourced from hemp containing less than 0.3% Delta-9 THC. Currently, Delta-10 THC is legal in most states. However, as with Delta-8, some states have outlawed Delta-10, so customers need to check local laws before purchasing these products. 

Comparing Delta 10 to Delta 8 and Delta 9 THC Molecules

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What Is HHC?

HHC (hexahydrocannabinol) is a hydrogenated derivative of Delta-9 THC. It does not occur naturally in hemp and cannabis plants. HHC products are semi-synthetically produced from cannabis extracts via a “hydrogenation” process.

HHC Experience

HHC users report a gradual, euphoric high followed by a smooth, calming experience. Many say it produces a less energetic high than typical sativas and is more cerebral and other-worldly. 

HHC compared to Delta-9: Consumers observe that HHC induces less-potent psychoactive effects than conventional Delta-9 THC. Still, some say HHC lasts much longer than Delta-9 (up to 12 hours).

Molecular Structure

HHC is not a tetrahydrocannabinol like Delta-8, Delta-9, or Delta-10. HHC belongs to a different chemical class known as hexahydrocannabinol. HHC has no double carbon bonds and is completely saturated, or fully hydrogenated. The hydrogen molecules in HHC also make it more stable, allowing HHC products to withstand oxidation, heat, and ultraviolet light better than THC.

Molecule Type: Hydrogenated derivative of THC. Also considered a THC analog compound.

How Are HHC Products Made?

HHC is typically made from Delta-8 THC through a process called hydrogenation. Producers start with hemp-derived CBD, which they convert to Delta-8. Then they use two active catalysts (typically heavy metals) to break apart Delta-8’s double-atom bonds and insert two hydrogen atoms, converting Delta-8 THC to HHC. 

HHC Hemp and Cannabis Products

HHC is a recent entry into the hemp market, so fewer product offerings exist. Two common HHC product types on the market currently include: 

  • Edibles 
  • Vape cartridges

HHC Legality

HHC is federally legal because it is a hemp derivative covered under the 2018 Farm Bill. However, as state and federal agencies continue to ban Delta-8 THC and other synthetic cannabinoids, some have also banned analogs like HHC

What Is THCOa (also called THCO)?

THCOa, often called THCO or THC-O, is an exotic cannabinoid that some users report is three times as potent as Delta-9. THC-O acetate does not naturally occur in hemp or cannabis plants. As a result, the DEA recently issued an opinion that it does not fall under the Farm Bill's hemp definition.

THCO Experience

THCO is an incredibly potent cannabinoid that produces intense euphoria and viscerally relaxing effects. Many consider THCO more of an evening substance because of its physically sedating properties. In larger doses, some say THC-O can be borderline psychedelic with potent couch-lock effects. 

THCO compared to Delta-9

THCO is a more potent analog of Delta-9 THC, meaning its psychedelic effects can be more intense. It takes longer to kick in, but the consensus says that THCO is around three times more potent than traditional Delta-9 THC. Some claims suggest that THCO is more bioavailable than other forms of THC, meaning more THCO makes it to the bloodstream. 

Molecular Structure

Commercial THCO products typically share the same base structure as Delta-8 THC. However, THCO is an acetylated version created by taking Delta-8 and binding it with acetic anhydride, a high-inflammable and colorless liquid used to make fibers, plastics, pharmaceuticals, and dyes.

Molecule Type: Acetylated derivative of THC. Also considered a THC analog. 

How Are THCO Products Made?

Manufacturers synthesize THC-O through a chemical process. First, they start with hemp-derived Delta-8 or Delta-9 THC. Then they combine the THC molecules with acetic anhydride to convert Delta-8 to THC-O. 

THCO Hemp and Cannabis Products

THCO is a relatively recent cannabinoid to hit the market. Most THC-O products feature a blend of other hemp-derived cannabinoids and mainly include: 

  • Vape cartridges
  • Gummies
  • Distillate

THCO Legality

The DEA recently issued a statement that Delta-8 and Delta-9 THCO fall under the Controlled Substances act because they don't occur naturally in hemp plants. It remains unclear whether the DEA will do anything to enforce this opinion. Likely, brands will continue operating in a legal gray area.

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