ACS Laboratory stands out among cannabis testing labs because it leads with clinical precision and commitment to safety, from cannabis testing across the entire botanical and fungi spectrum. Cannabis, hemp, mushroom, and kratom brands across the U.S. and globally trust ACS to deliver accurate results that optimize products from concept to creation. 

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1. A True Pioneer in Cannabis Testing

ACS Laboratory performed the first legal cannabis test in Florida in 2017. Today, nine laboratories are approved to operate statewide. Only ACS originated as a DEA-registered clinical facility. That distinction matters. It brought hospital-grade protocols, a deep scientific team, and proven quality controls to a cannabis industry still defining its rules. 

ACS has also helped shape cannabis compliance across the state. As Florida’s policies evolve, the lab continuously updates its testing panels and client support systems to meet shifting rules. The team regularly consults with industry groups, product developers, and regulators to improve methodology and educate brands about risk mitigation.

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2. Experts Across the Entire Plant and Fungi Space

ACS serves cannabis and hemp brands with precision. However, its expertise goes much further. The laboratory tests kratom, functional mushrooms, psychedelic mushrooms, and complex finished products across all categories. ACS has validated protocols for tinctures, vapes, beverages, topicals, and capsules. This breadth of service makes ACS the ideal partner for brands developing diverse botanical and fungi formulas.

Clients range from early-stage startups to international manufacturers. Many of them formulate hybrid products that include cannabinoids alongside nootropics and adaptogens. ACS supports this diversity with customized testing solutions and dedicated account management that adapts to each brand’s goals.

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3. Built on Scientific Rigor and Operational Scale

ACS operates from a 20,000-square-foot, DEA-registered, CLIA-licensed, ISO/IEC 17025:2017-accredited facility—the largest cannabis and botanical testing lab in the eastern U.S. The scientific team includes clinical chemists, microbiologists, and regulatory experts. The lab uses state-of-the-art LC-MS/MS and GC-MS instruments for ultra-sensitive analysis. 

Together, this infrastructure ensures fast turnaround times and highly refined results.

The lab processes thousands of samples weekly using lean workflows and digital reporting systems. Clients receive user-friendly COAs with QR-code integration and optional blockchain tracking. ACS’s secure data infrastructure ensures complete traceability across every test.

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4. An Industry Trailblazer That Keeps Innovating

ACS has earned 82 Emerald Test Badges for hemp and cannabis testing excellence. These awards confirm reliability in cannabinoid potency, pesticide, solvent, and microbiological testing. 

The lab also leads with technical innovation, including proprietary stability testing for cannabis inhalers and transdermal patches, nanoemulsion validation, cannabinoid fingerprinting, and full panels for infused beverages.

ACS collaborates with product developers to anticipate emerging needs and validate new ingredients. In recent years, the lab developed early detection methods for contaminants in hemp-derived vaporized liquids, semi-synthetic extracts, and biomass. These include heavy metals, vitamin E acetate, and plant growth regulators. 

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→ Explore ACS's complete testing services. 

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5. Innovation-Driven Testing for Tomorrow’s Products

ACS invests heavily in R&D to support product evolution as the market expands into novel cannabinoids and plant/fungi alkaloids. Its custom potency panels include THCV, HHC (both 9R- and 9S- diastereomers), and delta-8, rare tryptamine analogs (like 4-HO-TMT and aeruginascin), and kratom alkaloids like 7-hydroxymitragynine. 

ACS also performs matrix validation for non-traditional formats like nanoencapsulated tinctures, emulsified edibles, and powdered actives. This data allows brands to understand how stability, potency, and bioavailability interact over time and under various storage conditions.

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6. Specialized Kratom Testing That Sets the Standard

ACS offers the most comprehensive kratom testing panel in the U.S. The lab analyzes eight key alkaloids, mitragynine, paynantheine, speciogynine, speciociliatine, 7-OH-Mitragynine, mitraphylline, isorhycophylline, and corynoxine to help brands understand potency and safety. ACS also screens kratom products for heavy metals, residual solvents, pesticides, pathogens, and adulterants. This complete approach ensures that kratom manufacturers meet rising state regulations and earn consumer trust.

ACS collaborates with researchers, including Dr. Christopher McCurdy from the University of Florida’s College of Pharmacy, to standardize kratom data and provide reference materials. This work lays the foundation for future quality standards and public health protections in a rapidly evolving market.

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7. Comprehensive Hemp and CBD Testing Across 50 States

ACS is USDA-compliant for hemp and approved in all 50 states, including Puerto Rico. Additionally, ACS is certified to test hemp in seven states with their own programs, including Texas, Florida, Colorado, Georgia, Louisiana, New York and Pennsylvania. Each of these programs carries distinct testing requirements, and ACS has built the nation's most comprehensive hemp testing panel to meet and exceed them.

Its National Hemp Testing Panel includes cannabinoid potency, terpene profiles, mycotoxins, residual solvents, heavy metals, pesticides, and microbiological safety. ACS also verifies label claims and conducts shelf-life testing to ensure long-term compliance. Its labeling accuracy and ability to detect trace contaminants protect clients from recalls, warning letters, and consumer backlash.

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8. Pioneering Mushroom Testing—Functional and Psychedelic

ACS Laboratory supports psychedelic and functional mushroom brands with dedicated testing protocols tailored to each category. With DEA registration and forensic-level standards, the lab ensures safety, innovation, and compliance in this fast-growing space.

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Psychedelic Mushrooms
ACS quantifies a wide range of active tryptamines, including psilocybin, psilocin, baeocystin, norbaeocystin, norpsilocin, aeruginascin, and 4-HO-TMT. These validated methods support clinical research, formulation development, and accurate dosing. (see full panel details)

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Amanita Muscaria
ACS provides targeted testing for muscimol and ibotenic acid to support the growing market for Amanita muscaria products. Accurate analysis is critical due to these compounds' narrow safety margin and distinct pharmacology. (see full panel details)

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Functional Mushrooms
ACS tests medicinal mushrooms like Lion’s Mane, Reishi, Turkey Tail, Chaga, Cordyceps, Maitake, and Shiitake for beneficial compounds, including beta-glucans and ergothioneine. (see full panel details)

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Safety Testing Across All Categories
ACS screens all mushroom products for pesticides, heavy metals, residual solvents, mycotoxins, and microbiological contamination using the strictest state compliance standards. 

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9. More Than a Lab—A Partner in Progress

ACS provides accurate results and expert guidance on regulatory compliance, product formulation, and test selection. Scientists work directly with growers, extractors, and brand teams to support R&D and troubleshoot challenges. ACS also invests in education through compliance guides and client data tools, like the proprietary strain trends report. Its mission is to empower clients to launch confidently and scale with integrity.

Client relationships often span years. They entail ongoing collaboration through product reformulations, new market entries, and compliance audits. ACS’s white-glove service model ensures that every brand, from start-up to multinational, receives the attention it needs to succeed.

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The Bottom Line

ACS Laboratory stands out because it delivers more than compliance. It brings clinical discipline to cannabis, advanced science to emerging categories, and deep partnership to every product lifecycle stage. The most ambitious cannabis, hemp, kratom, and mushroom brands work with ACS to shape the future of quality and safety standards. 

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→ Get a quote or speak to a testing expert.